MYPT1的减少在老年自发性高血压大鼠肠系膜动脉NO介导的血管扩张功能受损中起关键作用

The decrease of MYPT1 is critical for the impairment of NO-mediated vasodilation in the mesenteric artery of aging spontaneously hypertensive rats

体重波动与射血分数保留型心力衰竭患者预后的相关性

Association of Body-Weight Fluctuation with Outcomes in Heart Failure with Preserved Ejection Fraction

SERCA2 Cys674（C674）位点替代加重心脏纤维化：心脏成纤维细胞向心脏肌成纤维细胞转化

Substitution of SERCA2 Cys674 aggravates cardiac fibrosis by promoting the transformation of cardiac fibroblasts to cardiac myofibroblasts

蛭龙活血通瘀胶囊化学成分分析及其治疗心肌缺血再灌注损伤的潜在机制研究

Analysis of chemical constituents of Zhilong Huoxue Tongyu Capsule and its potential mechanism in the treatment of myocardial ischemia-reperfusion injury

普氏粪杆菌通过调节肠道微生物-丁酸-GPR43轴改善肾脏炎症和损伤

Faecalibacterium Prausnitzii ameliorates renal inflammation and injury by modulating the gut microbiota-butyrate-GPR43 axis

hsa_circ_0025573-miR-133b-MMP9互作网络在房颤发生中的作用和机制研究

The role and mechanism of hsa_circ_0025573-miR-133b-MMP9 interaction network in atrial fibrillation

金合欢素通过TGF-β1/Smad信号通路减轻自发性高血压大鼠(SHR)心肌纤维化

Acacetin alleviates cardiac fibrosis in SHR via TGF-β1/Smad signal pathway

基于代谢组学和脂质组学的蛭龙活血通瘀胶囊抗动脉粥样硬化分子机制研究

Molecular mechanism of Zhilong Huoxue Tongyu Capsules against atherosclerosis based on metabolomics and lipidomics

心脏靶向性基因工程外泌体改善压力超负荷诱导的小鼠心肌肥厚

Cardiac-targeted genetically engineered exosomes ameliorate pressure overload-induced myocardial hypertrophy in mice

利用人胚胎干细胞体外分化模型分析纳米二氧化钛的毒性及其作用机制

Toxicity and mechanism of nano-titanium dioxide analyzed by in vitro differentiation model of human embryonic stem cells

长期访视血压变异性与中年亚临床肾损害和蛋白尿的关系：一项30年前瞻性队列研究

Associations of long-term visit-to-visit blood pressure variability with subclinical renal damage and albuminuria in midlife: a 30-year prospective cohort study

SERCA2半胱氨酸674位点替换通过诱导内质网应激和细胞凋亡促进主动脉瘤的形成

Substitution of SERCA2 Cys674 accelerates aortic aneurysm by inducing endoplasmic reticulum stress and promoting cell apoptosis

敲入突变揭示SERCA2半胱氨酸674通过氧化应激信号控制血压

Knock-in mutation reveals SERCA2 cysteine 674 in controlling blood pressure via oxidant stress signaling pathway

新肽ATH-1与CaMKII相互作用的分子对接分析

Molecular docking analysis of interaction between ATH-1 and CaMKII

脂肪干细胞的光活化促进外泌体生成并改善肥胖相关的 M2 极化巨噬细胞

Photoactivation of adipose stem cells promotes exosome production and ameliorates obesity-associated M2-polarized macrophages

酵母微囊仿生体在移植排斥反应诊疗应用中的研究

Application of yeast microcapsule biomimetic in diagnosis and treatment of transplant rejection

孕期昼夜节律紊乱诱发雄性小鼠心脏病理性重构的调控机制研究

Prenatal disruption of the circadian clock increases left ventricular remodeling in male mice

转录因子CREB在心肌梗死后纤维化中的作用及分子机制

The role and molecular mechanism of transcription factor CREB in fibrosis after myocardial infarction

二甲双胍对丙酮醛引起的人内皮细胞氧化损伤及凋亡的影响

Effects of metformin on oxidative damage and apoptosis of human endothelial cells induced by glyoxal

基于生信分析结合动物实验验证玄府理论指导下的中药制剂抗高血压心肌纤维化可能的作用机制

Based on bioinformatics analysis combined with animal experiments to verify the possible mechanism of traditional Chinese medicine preparations against hypertensive myocardial fibrosis under the guidance of Xuanfu theory

探究血管内皮屏障在主动脉夹层中的作用及机制研究

Exploration on the role and mechanism of vascular endothelial barrier in aortic dissection

心肌缺血再灌注重构中的单细胞信号通路和表观遗传图谱

Single-cell signaling pathway and epigenetic map during myocardial ischemia-reperfusion remodeling

白介素增强结合因子3（ILF3）调节一氧化氮产生参与高血压交感亢进的作用研究

The role of interleukin-enhancing binding factor 3 (ILF3) in regulating nitric oxide production and participating in hypersympathetic hypertension

肌浆网/内质网钙ATP酶2（SERCA2）中C674失活促进肺血管重构的机制研究

Mechanism of inactivation of C674 in sarcoplasmic reticulum/endoplasmic reticulum calcium ATPase 2 (SERCA2) promoting pulmonary vascular remodeling

MIR-339-3p加剧由AT1-AA通过下调BKα蛋白表达而诱发的血管炎症

miR-339-3p aggravates vascular inflammation induced by AT1-AA via down-regulating BKα protein expression

Mas相关G蛋白偶联受体D（MrgD）的入核通过G蛋白偶联受体αi亚基（Gαi）介导的信号通路诱导病理性心脏重构的发生

MAS associated G protein coupled receptor D (MrgD) enters the nucleus through G protein coupled receptor α I subunit (Gαi Mediated signaling pathway induces pathological cardiac remodeling

血压和交感传出的中枢调控常用研究方法

Common research methods of central regulation of blood pressure and sympathetic efference